Larry Matherly : rechercher sur Z-Library

Campagne de collecte 15 septembre 2024 – 1 octobre 2024 C'est quoi, la collecte de fonds?

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Campagne de collecte 15 septembre 2024 – 1 octobre 2024

Z-Library est une des plus grandes bibliothèques en ligne dans le monde, avec le stockage de plus de 17,000,000 livres et plus de 84,837,000 articles. Nous encourageons l'accès libre de chacun à la littérature. Aujourd'hui (15 septembre 2024) nous faisons un appel de fonds à tous ceux qui veulent contribuer encore plus au soutien et au développement de notre projet.

Les téléchargements SANS LIMITE sont aussi (au cours de 31 jours après la date de don) disponibles pour TOUS les utilisateurs qui soient en mesure de soutenir le projet pendant la période de collecte de fonds jusqu'au 1 octobre 2024.

C'est quoi, la collecte de fonds?En savoir plus

Livres
Articles (96)
Les plus populaires
Liste
- Liste
- Tableau

1

Book Reviews

Hurlock, Kathryn, Rogers, Clifford J., Beard, Jonathan, Finney, Patrick, Foot, M.R.D., Parsons, Charlie, Schecter, Jerrold L., Theoharis, Athan, Lamanna, Larry, Zuhur, Sherifa, Mathers, Jennifer G., R

Journal:

Intelligence & National Security

Année:

2011

Langue:

english

Fichier:

PDF, 242 KB

english, 2011

2

Book reviews

Thornton, Martin, Morris, Peter, Travers, Tim, Sheffy, Yigal, Hannant, Larry, Thurlow, Richard C., Imlay, Talbot, Parkinson, Lt‐Cdr Frederick, Mathers, Jennifer G., Breslin, Shaun, Başak, Cengiz, Spie

Journal:

Intelligence & National Security

Année:

1995

Langue:

english

Fichier:

PDF, 1.52 MB

english, 1995

3

Association between prenatal pesticide exposures and the generation of leukemia-associated T(8;21)

Katherine M. LaFiura, Dawn M. Bielawski, Norberto C. Posecion Jr., Enrique M. Ostrea Jr., Larry H. Matherly, Jeffrey W. Taub, Yubin Ge

Journal:

Pediatric Blood & Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 172 KB

english, 2007

4

[Vitamins & Hormones] Folic Acid and Folates Volume 79 || Chapter 5 Structure and Function of the Reduced Folate Carrier

Matherly, Larry H.

Année:

2008

Langue:

english

Fichier:

PDF, 522 KB

english, 2008

5

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Orlando, Florida , USA (Wednesday 24 May 2006)] Space Telescopes and Instrumentation I: Optical, Infrared, and Millimeter - Coronagraphic Exploration Camera (CorECam)

Clampin, Mark, Mather, John C., MacEwen, Howard A., Lyon, Richard, Petro, Larry, de Graauw, Mattheus W. M., Seager, Sara, Marley, Mark, Melnick, Gary, Weinberger, Alycia, Woodruff, Robert, Horner, Sco

Année:

2006

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2006

6

Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolates Via Cellular Uptake by Folate Receptor α and the Proton-coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis

Ravindra, Manasa, Wallace-Povirk, Adrianne, Karim, Mohammad A., Wilson, Mike R., O'Connor, Carrie E, White, Kathryn, Kushner, Juiwanna, Polin, Lisa A., George, Christina, Hou, Zhanjun, Matherly, Larry

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2018

7

P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene

Andrew J. Gifford, Maria Kavallaris, Janice Madafiglio, Larry H. Matherly, Bernard W. Stewart, Michelle Haber, Murray D. Norris

Journal:

International Journal of Cancer

Année:

1998

Langue:

english

Fichier:

PDF, 128 KB

english, 1998

8

Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia

Yotam Kaufman, Stavit Drori, Peter D. Cole, Barton A. Kamen, Jenny Sirota, Ilan Ifergan, Myriam Weyl Ben Arush, Ronit Elhasid, Dvora Sahar, Gert Jan L. Kaspers, Gerrit Jansen, Larry H. Matherly, Gideo

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 257 KB

english, 2004

9

Relationship of p15 and p16 gene alterations to elevated dihydrofolate reductase in childhood acute lymphoblastic leukaemia

Sanjay J. Shah, Jeffrey W. Taub, Teah L. Witt, Brad H. Pollock, Bee Ching Ding, Daniel S. Moore, Michael Amylon, Jeanette Pullen, Yaddanapudi Ravindranath, Larry H. Matherly

Journal:

British Journal of Haematology

Année:

2001

Langue:

english

Fichier:

PDF, 159 KB

english, 2001

10

Preface

Larry H. Matherly

Journal:

Cancer and Metastasis Reviews

Année:

2007

Langue:

english

Fichier:

PDF, 57 KB

english, 2007

11

Human reduced folate carrier: translation of basic biology to cancer etiology and therapy

Larry H. Matherly, Zhanjun Hou, Yijun Deng

Journal:

Cancer and Metastasis Reviews

Année:

2007

Langue:

english

Fichier:

PDF, 599 KB

english, 2007

12

A method for the synchronization of cultured cells with aphidicolin: Application to the large-scale synchronization of L1210 cells and the study of the cell cycle regulation of thymidylate synthase and dihydrofolate reductase

Larry H. Matherly, John D. Schuetz, Eric Westin, I.David Goldman

Journal:

Analytical Biochemistry

Année:

1989

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1989

13

Activity of Dendrimer−Methotrexate Conjugates on Methotrexate-Sensitive and -Resistant Cell Lines

Gurdag, Sezen, Khandare, Jayant, Stapels, Sarah, Matherly, Larry H., Kannan, Rangaramanujam M.

Journal:

Bioconjugate Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 215 KB

english, 2006

14

Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cells

Chengzhi Xie, Holly Edwards, Salvatore B. LoGrasso, Steven A. Buck, Larry H. Matherly, Jeffrey W. Taub, Yubin Ge

Journal:

Pediatric Blood & Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 292 KB

english, 2012

15

Transcriptional regulation of the human reduced folate carrier promoter C: synergistic transactivation by Sp1 and C/EBP β and identification of a downstream repressor

Scott G. Payton, Johnathan R. Whetstine, Yubin Ge, Larry H. Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2005

Langue:

english

Fichier:

PDF, 886 KB

english, 2005

16

Transcriptional regulation of the human reduced folate carrier A1/A2 promoter: Identification of critical roles for the USF and GATA families of transcription factors

Scott G. Payton, Mingjun Liu, Yubin Ge, Larry H. Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2005

Langue:

english

Fichier:

PDF, 474 KB

english, 2005

17

Effects of 5′ untranslated region diversity on the posttranscriptional regulation of the human reduced folate carrier

Scott G. Payton, Christina L. Haska, Robin M. Flatley, Yubin Ge, Larry H. Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2007

Langue:

english

Fichier:

PDF, 774 KB

english, 2007

18

Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione

Lawrence H. Lash, David A. Putt, Feng Xu, Larry H. Matherly

Journal:

Chemico-Biological Interactions

Année:

2007

Langue:

english

Fichier:

PDF, 364 KB

english, 2007

19

Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells

Bee Ching Ding, Teah L. Witt, Bharati Hukku, Henry Heng, Long Zhang, Larry H. Matherly

Journal:

Biochemical Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2001

20

Gene Amplification and Increased Expression of the Reduced Folate Carrier in Transport Elevated K562 Cells

So C Wong, Long Zhang, Susan A Proefke, Bharati Hukku, Larry H Matherly

Journal:

Biochemical Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 457 KB

english, 1998

21

Synergistic regulation of human cystathionine-β-synthase-1b promoter by transcription factors NF-YA isoforms and Sp1

Yubin Ge, Tanya L Jensen, Larry H Matherly, Jeffrey W Taub

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

2002

Langue:

english

Fichier:

PDF, 376 KB

english, 2002

22

Structure and organization of the human reduced folate carrier gene

Long Zhang, So C Wong, Larry H Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1998

Langue:

english

Fichier:

PDF, 166 KB

english, 1998

23

Identification of the enol tautomer of imidazolone propionate as the urocanase reaction product

Larry H. Matherly, Allen T. Phillips

Journal:

Archives of Biochemistry and Biophysics

Année:

1983

Langue:

english

Fichier:

PDF, 389 KB

english, 1983

24

Evidence for a localized conversion of endogenous tetrahydrofolate cofactors to dihydrofolate as an important element in antifolate action in murine leukemia cells

Larry H. Matherly, Stephen P. Muench

Journal:

Biochemical Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1990

25

Determinants of the disparate antitumor activities of (6R)-5,10-dideaza-5,6,7,8-tetrahydrofolate and methotrexate toward human lymphoblastic leukemia cells, characterized by severely impaired antifolate membrane transport

Larry H. Matherly, Susan M. Angeles, John J. McGuire

Journal:

Biochemical Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1993

26

Role of N-glycosylation in the structure and function of the methotrexate membrane transporter from CCRF-CEM human lymphoblastic leukemia cells

Larry H. Matherly, Susan M. Angeles

Journal:

Biochemical Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 442 KB

english, 1994

27

Diurnal variation in gonadotropic potency of the adenohypophysis of Japanese quail (Coturnix coturnix japonica)

Katuhide Tanaka, Wilbor O. Wilson, F.Benjamin Mather, Larry Z. McFarland

Journal:

General and Comparative Endocrinology

Année:

1966

Langue:

english

Fichier:

PDF, 301 KB

english, 1966

28

Parameters for individualizing systemic therapy in non-small cell lung cancer

Shirish M. Gadgeel, Michele L. Cote, Ann G. Schwartz, Larry H. Matherly, Antoinette Wozniak, Gerold Bepler

Journal:

Drug Resistance Updates

Année:

2010

Langue:

english

Fichier:

PDF, 385 KB

english, 2010

29

Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces

Jordan M. Nechvatal, Jeffrey L. Ram, Marc D. Basson, Phanramphoei Namprachan, Stephanie R. Niec, Kawsar Z. Badsha, Larry H. Matherly, Adhip P.N. Majumdar, Ikuko Kato

Journal:

Journal of Microbiological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 578 KB

english, 2008

30

A humanized mouse model for the reduced folate carrier

David Patterson, Christine Graham, Christina Cherian, Larry H. Matherly

Journal:

Molecular Genetics and Metabolism

Année:

2008

Langue:

english

Fichier:

PDF, 454 KB

english, 2008

31

Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis

Xiang Y Liu, Larry H Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2002

Langue:

english

Fichier:

PDF, 305 KB

english, 2002

32

Identification of lysine-411 in the human reduced folate carrier as an important determinant of substrate selectivity and carrier function by systematic site-directed mutagenesis

Teah L Witt, Larry H Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2002

Langue:

english

Fichier:

PDF, 216 KB

english, 2002

33

Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier

So C. Wong, Long Zhang, Susan A. Proefke, Larry H. Matherly

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1998

Langue:

english

Fichier:

PDF, 369 KB

english, 1998

34

Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3- d ]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry †

Deng, Yijun, Zhou, Xilin, Kugel Desmoulin, Sita, Wu, Jianmei, Cherian, Christina, Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 313 KB

english, 2009

35

The cellular pharmacology of methotrexate

I.David Goldman, Larry H. Matherly

Journal:

Pharmacology & Therapeutics

Année:

1985

Langue:

english

Fichier:

PDF, 2.16 MB

english, 1985

36

Metabolism of the diaminoantifolates: Biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolates

Larry H. Matherly, Richard L. Seither, I. David Goldman

Journal:

Pharmacology & Therapeutics

Année:

1987

Langue:

english

Fichier:

PDF, 2.49 MB

english, 1987

37

Role of MRP4 and MRP5 in biology and chemotherapy

Janardhan Sampath, Masashi Adachi, Sigrid Hatse, Lieve Naesens, Jan Balzarini, Robin Flatley, Larry Matherly, John Schuetz

Journal:

The AAPS Journal

Année:

2002

Langue:

english

Fichier:

PDF, 377 KB

english, 2002

38

Human k562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity

So C. Wong, Ryan McQuade, Susan A. Proefke, Alok Bhushan, Larry H. Matherly

Journal:

Biochemical Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1997

39

[Progress in Nucleic Acid Research and Molecular Biology] Progress in Nucleic Acid Research and Molecular Biology Volume 67 Volume 67 || Molecular and cellular biology of the human reduced folate carrier

Matherly, Larry H.

Année:

2001

Langue:

english

Fichier:

PDF, 4.03 MB

english, 2001

40

Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for Cellular Uptake by High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier

Wang, Lei, Cherian, Christina, Kugel Desmoulin, Sita, Mitchell-Ryan, Shermaine, Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012

41

New insights into Notch1 regulation of the PI3K–AKT–mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Hales, Eric C., Taub, Jeffrey W., Matherly, Larry H.

Journal:

Cellular Signalling

Année:

2014

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2014

42

Up-regulation of intestinal folate uptake process in dietary folate deficiency: Functional and molecular mechanisms

Said, Hamid M., Chatterjee, Nabendu, Haq, Riaz, Subramanian, Veedamali, Ortiz, Alvaro, Matherly, Larry, Sirotnak, Francis, Halsted, Charles

Journal:

Gastroenterology

Année:

2000

Langue:

english

Fichier:

PDF, 190 KB

english, 2000

43

Discovery of 5-Substituted Pyrrolo[2,3- d ]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity

Mitchell-Ryan, Shermaine, Wang, Yiqiang, Raghavan, Sudhir, Ravindra, Manasa Punaha, Hales, Eric, Orr, Steven, Cherian, Christina, Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.92 MB

english, 2013

44

Tumor-Targeting with Novel Non-Benzoyl 6-Substituted Straight Chain Pyrrolo[2,3- d ]pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and Inhibition of de Novo Purine Nucleotide Biosynthesis

Wang, Yiqiang, Cherian, Christina, Orr, Steven, Mitchell-Ryan, Shermaine, Hou, Zhanjun, Raghavan, Sudhir, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.42 MB

english, 2013

45

Methotrexate Pharmacology and Resistance in Childhood Acute Lymphoblastic Leukemia

Matherly, Larry H., Taub, Jeffrey W.

Journal:

Leukemia and Lymphoma

Année:

1996

Langue:

english

Fichier:

PDF, 1.00 MB

english, 1996

46

A covalent NAD intermediate in the urocanase reaction

Matherly, Larry H., DeBrosse, Charles W., Phillips, Allen T.

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 728 KB

english, 1982

47

Substrate-mediated inactivation of urocanase from Pseudomonas putida. Evidence for an essential sulfhydryl group

Matherly, Larry H., Phillips, Allen T.

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 586 KB

english, 1980

48

Transient-state kinetic analysis of urocanase

Matherly, Larry H., Johnson, Kenneth A., Phillips, Allen T.

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 509 KB

english, 1982

49

Mechanism of urocanase as studied by deuterium isotope effects and labeling patterns

Egan, Rita M., Matherly, Larry H., Phillips, Allen T.

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 749 KB

english, 1981

50

Synthesis and Discovery of High Affinity Folate Receptor-Specific Glycinamide Ribonucleotide Formyltransferase Inhibitors with Antitumor Activity

Deng, Yijun, Wang, Yiqiang, Cherian, Christina, Hou, Zhanjun, Buck, Steven A., Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 327 KB

english, 2008